Wednesday, March 14, 2012

President Waheed appoints fisheries minister, eight state ministers

President Waheed appoints fisheries minister, eight state ministers thumbnail

President Dr Mohamed Waheed appointed Ahmed Shafeeu as Minister of Fisheries and Agriculture. Shafeeu was formerly Director General at the Education Ministry.

The appointment of Shafeeu fills the last post in Dr Waheed?s cabinet.

Dr Waheed also appointed eight state ministers, including Hussain Maniku Dhon Maniku (Home Affairs), retired Deputy Commissioner of Police Mohamed Fayaz (Home Affairs), December 23 protest organiser and spokesperson Abdulla Mohamed (Home Affairs), Ali Shareef Mohamed (Health and Family), Dr Aishath Rameela (Health and Family), Hassan Saeed Hussain (Foreign Affairs), Abdulla Ziyad (Housing and Environment), and Abdul Matheen Mohamed (Housing and Environment).


Source: http://minivannews.com/news-in-brief/president-waheed-appoints-fisheries-minister-eight-state-ministers-33203

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Saturday, March 10, 2012

Heavy Rain creators produce 'Kara' PS3 tech-demo (video)

Heavy Rain creator David Cage was showing off Quantic Dream's new game engine at GDC, which includes an innovative new performance-capture technology the company's developed. He's directed a seven-minute original short called Kara, which is the story of a female android as she becomes self-aware. Unlike traditional game production methods, this technology is able to record face and body movements at the same time as recording the actors voice -- ensuring natural and consistent performances from the characters. Actress Valorie Curry wore 90 sensors on her face, unlike in, say, Avatar, where the performers wore head-mounted cameras. Cage promises that the short is nothing more than a demo (it was rendered in real-time on a PlayStation 3) and none of these elements will appear in his next game. You can catch the impressive-looking footage after the break with one disclaimer: there's nudity throughout and a reference to adult themes, okay?

Continue reading Heavy Rain creators produce 'Kara' PS3 tech-demo (video)

Heavy Rain creators produce 'Kara' PS3 tech-demo (video) originally appeared on Engadget on Thu, 08 Mar 2012 19:03:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/03/08/quantic-dream-kara-demo/

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Friday, March 9, 2012

Cancer therapy: Drugs that get under your skin

Cancer therapy: Drugs that get under your skin [ Back to EurekAlert! ] Public release date: 8-Mar-2012
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Contact: Dr. Ralf Gutzmer
gutzmer.ralf@mh-hannover.de
Deutsches Aerzteblatt International

Skin problems are the most common adverse effects from new anti-cancer drugs. Ralf Gutzmer, from the Hannover Medical School (MHH), and co-authors now summarize the current state of knowledge in the recent edition of Deutsches rzteblatt International (Dtsch Arztebl Int 2012; 109(8): 133-40).

Adverse effects of the skin include rashes, nail problems, and the hand-foot syndrome. The substance class of multikinase inhibitors causes such cutaneous adverse effects in up to 34% of patients. The proportion of patients with adverse effects is even higher for the selective kinase inhibitors, such as epidermal growth factor receptor (EGFR) inhibitors and inhibitors of mutated BRAF, with up to 90% affected, and for immunotherapeutics such as the CTLA-4 antibody, with up to 68% affected.

Such adverse effects can be severe, painful, or lead to psychological discomfort due to their localization on visible areas of the body, and this can affect patients' willingness to continue treatment. However, adverse effects can also be associated with a patient's positive response to therapy, as is the case for the EGFR inhibitors.

Early recognition and treatment of cutaneous adverse effects are critical to successfully implementing anti-cancer drug therapies. Achieving this requires on the one hand the primary treating physician, and on the other, an intensive, interdisciplinary collaboration involving dermatologists.

###

http://www.aerzteblatt.de/pdf.asp?id=122847


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Cancer therapy: Drugs that get under your skin [ Back to EurekAlert! ] Public release date: 8-Mar-2012
[ | E-mail | Share Share ]

Contact: Dr. Ralf Gutzmer
gutzmer.ralf@mh-hannover.de
Deutsches Aerzteblatt International

Skin problems are the most common adverse effects from new anti-cancer drugs. Ralf Gutzmer, from the Hannover Medical School (MHH), and co-authors now summarize the current state of knowledge in the recent edition of Deutsches rzteblatt International (Dtsch Arztebl Int 2012; 109(8): 133-40).

Adverse effects of the skin include rashes, nail problems, and the hand-foot syndrome. The substance class of multikinase inhibitors causes such cutaneous adverse effects in up to 34% of patients. The proportion of patients with adverse effects is even higher for the selective kinase inhibitors, such as epidermal growth factor receptor (EGFR) inhibitors and inhibitors of mutated BRAF, with up to 90% affected, and for immunotherapeutics such as the CTLA-4 antibody, with up to 68% affected.

Such adverse effects can be severe, painful, or lead to psychological discomfort due to their localization on visible areas of the body, and this can affect patients' willingness to continue treatment. However, adverse effects can also be associated with a patient's positive response to therapy, as is the case for the EGFR inhibitors.

Early recognition and treatment of cutaneous adverse effects are critical to successfully implementing anti-cancer drug therapies. Achieving this requires on the one hand the primary treating physician, and on the other, an intensive, interdisciplinary collaboration involving dermatologists.

###

http://www.aerzteblatt.de/pdf.asp?id=122847


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-03/dai-ctd030812.php

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Tuesday, March 6, 2012

Obama holds news conference, unveils housing plan

President Barack Obama meets with Israeli Prime Minister Benjamin Netanyahu, Monday, March, 5, 2012, in the Oval Office of the White House in Washington. (AP Photo/Pablo Martinez Monsivais)

President Barack Obama meets with Israeli Prime Minister Benjamin Netanyahu, Monday, March, 5, 2012, in the Oval Office of the White House in Washington. (AP Photo/Pablo Martinez Monsivais)

(AP) ? President Barack Obama is aiming mortgage relief at members of the military as well as homeowners with government-insured loans, the administration's latest efforts to address a persistent housing crisis.

In his first full news conference of the year Tuesday, Obama was to announce plans to let borrowers with mortgages insured by the Federal Housing Administration refinance at lower rates, saving the average homeowner more than $1,000 a year. Obama also was detailing an agreement with major lenders to compensate service members and veterans who were wrongfully foreclosed upon or denied lower interest rates.

A senior administration official described Obama's proposals to The Associated Press on the condition of anonymity to discuss them ahead of the announcement.

The efforts Obama is announcing do not require congressional approval and are limited in comparison with the vast expansion of government assistance to homeowners that he asked Congress to approve last month. That $5 billion to $10 billion plan would make it easier for more borrowers with burdensome mortgages to refinance their loans.

Obama is holding the news conference in the midst of a modestly improving economy. But international challenges as well as a stubbornly depressed housing market remain threats to the current recovery and to his presidency.

Obama has not held a full news conference since November. The White House scheduled this one on the same day as the 10-state Super Tuesday Republican presidential nominating contests. While aides insisted the timing was coincidental, it follows a pattern of Obama seeking the limelight when the attention is on the GOP.

The news conference comes amid a new sense of optimism at the White House. Obama's public approval ratings have inched up close to 50 percent. The president recently won an extension of a payroll tax cut that was a main element of his jobs plan for 2012. Economic signals suggest a recovery that is taking hold.

Still, he will probably face questions about the pace of the recovery. The unemployment rate in January was 8.3 percent, the highest it has been in an election year since the Great Depression. With rising gasoline prices threatening to slow the economy, Obama has also faced attacks from Republicans over his energy policy.

Iran's nuclear ambitions will also command attention in the aftermath of his meeting Monday with Israeli Prime Minister Benjamin Netanyahu. Tension over Iran has already contributed to higher oil prices, and Israel's threats of pre-emptive military strikes to prevent Tehran from building a nuclear bomb have dominated Washington discourse for weeks.

Other developments in the Middle East, where turmoil has soured some of the promise of last year's Arab Spring, are also likely to be addressed. Syria's bloody crackdown on protesters has increased pressure on Obama to intervene. Republican Sen. John McCain on Monday urged the United States to launch airstrikes against Syrian President Bashar Assad's regime to force him out of power.

Under the housing plans Obama was to announce Tuesday, FHA-insured borrowers would be able to refinance their loans at half the fee that the FHA currently charges. FHA borrowers who want to refinance now must pay a fee of 1.15 percent of their balance every year. Officials say those fees make refinancing unappealing to many borrowers. The new plan will reduce that charge to 0.55 percent.

With mortgage rates at about 4 percent, the administration estimates a typical FHA borrower with $175,000 still owed on a home could reduce monthly payments to $915 a month and save $100 a month more than the borrower would have under current FHA fees.

Though 2 million to 3 million borrowers would be eligible, the administration official would not speculate how many would actually seek to benefit from the program. The FHA provides mortgage insurance on loans made by FHA-approved lenders throughout the United States and its territories. The loans typically go to homeowners who do not have enough equity to qualify for standard mortgages. It is the largest insurer of mortgages in the world.

For service members and veterans, Obama will announce that major lenders will review foreclosures to determine whether they were done properly. If wrongly foreclosed upon, service members and veterans would be paid their lost equity and also be entitled to an additional $116,785 in compensation. That was a figure reached through an agreement with major lenders by the federal government and 49 state attorneys general.

Under the agreement, the lenders also would compensate service members who lost value in their homes when they were forced to sell them due to a military reassignment.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-03-06-Obama/id-69820d10930a4977aa73f469c9fafa96

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Monday, March 5, 2012

Storms demolish small towns in Ind., Ky.; 38 dead

Residents clean up their damaged house in Marysville, Ind., Saturday, March 3, 2012. Massive thunderstorms, predicted by forecasters for days, threw off dozens of tornadoes as they raced Friday from the Gulf Coast to the Great Lakes. Twisters crushed blocks of homes, knocked out cellphones and landlines, ripped power lines from broken poles and tossed cars, school buses and tractor-trailers onto roads made impassable by debris. (AP Photo/Nam Y. Huh)

Residents clean up their damaged house in Marysville, Ind., Saturday, March 3, 2012. Massive thunderstorms, predicted by forecasters for days, threw off dozens of tornadoes as they raced Friday from the Gulf Coast to the Great Lakes. Twisters crushed blocks of homes, knocked out cellphones and landlines, ripped power lines from broken poles and tossed cars, school buses and tractor-trailers onto roads made impassable by debris. (AP Photo/Nam Y. Huh)

In this aerial photo, a home is shown swept away Saturday, March 3, 2012, in Holton, Indiana, after a tornado swept through the town Friday. A string of violent storms demolished small towns in Indiana and cut off rural communities in Kentucky as an early season tornado outbreak killed more than 30 people, and the death toll rose as daylight broke on Saturday's search for survivors.(AP Photo/Al Behrman)

In this aerial photo, a television news helicopter flies over damaged homes Saturday, March 3, 2012, in Henryville, Indiana, after a tornado swept through the town Friday. A string of violent storms demolished small towns in Indiana and cut off rural communities in Kentucky as an early season tornado outbreak killed more than 30 people, and the death toll rose as daylight broke on Saturday's search for survivors(AP Photo/Al Behrman)

Sen. Rob Portman, R-Ohio, right, and Washington Township fire chief Dana Kellenberger, left, look over damage in the village of Moscow, Ohio, Saturday, March 3, 2012. Massive thunderstorms, predicted by forecasters for days, threw off dozens of tornadoes as they raced Friday from the Gulf Coast to the Great Lakes. Twisters crushed blocks of homes, knocked out cellphones and landlines, ripped power lines from broken poles and tossed cars, school buses and tractor-trailers onto roads made impassable by debris. (AP Photo/David Kohl)

Two men work to secure a tarp to cover the roof of a home along Highway 160 in Henryville, Ind., Saturday, March 3, 2012 as residents try to recover from the massive tornado touchdown Friday afternoon in the community of 2,000 in northern Clark County 20 miles north of Louisville, Ky. (AP Photo/Garry Jones)

(AP) ? Across the South and Midwest, survivors emerged Saturday to find blue sky and splinters where homes once stood, cars flung into buildings and communications crippled after dozens of tornadoes chainsawed through a region of millions, leveling small towns along the way.

At least 38 people were killed in five states, but a 2-year-old girl was somehow found alive and alone in a field near her Indiana home. Her family did not survive. A couple that fled their home for the safety of a restaurant basement made it, even after the storms threw a school bus into their makeshift shelter.

Saturday was a day filled with such stories, told as emergency officials trudged with search dogs past knocked-down cellphone towers and ruined homes looking for survivors in rural Kentucky and Indiana, marking searched roads and homes with orange paint. President Barack Obama offered federal assistance, and Ohio Gov. John Kasich declared an emergency Saturday.

The worst damage appeared centered in the small towns of southern Indiana and eastern Kentucky's Appalachian foothills. No building was untouched and few were recognizable in West Liberty, Ky., about 90 miles from Lexington, where two white police cruisers were picked up and tossed into City Hall.

"We stood in the parking lot and watched it coming," said David Ison, who raced into a bank vault with nine others to seek safety. "By the time it hit, it was like a whiteout."

In East Bernstadt, two hours to the southwest, Carol Rhodes clutched four VHS tapes she'd found in debris of her former home as she sobbed under a bright sun Saturday.

"It was like whoo, that was it," said Rhodes, 63, who took refuge with four family members in a basement bedroom that she had just refinished for a grandchild.

"Honey, I felt the wind and I said, 'Oh my God,' and then it (the house) was gone. I looked up and I could see the sky."

The spate of storms was the second in little more than 48 hours, after an earlier round killed 13 people in the Midwest and South, and the latest in a string of severe-weather episodes that have ravaged the American heartland in the past year.

Friday's violent storms touched down in at least a dozen states from Georgia to Illinois, killing 19 people in Kentucky, 14 in Indiana, three in Ohio, and one each in Alabama and Georgia.

The National Weather Service said the four twisters to hit Kentucky were the worst in the region in 24 years. In Indiana, an EF-4 tornado ? the second-highest on the Fujita scale that measures tornadic force ? packing 175 mph winds hit the town of Henryville, and stayed on the ground for more than 50 miles.

The storms scarred the landscape over hundreds of miles, leaving behind a trail of shredded sheet metal, insulation, gutted churches, crunched-up cars and even a fire hydrant.

The trailer that was once the home of Viva Johnson's mother was sitting in a graveyard on Saturday, covering the dead alongside downed trees and other debris. "You can't even tell where the headstones are," said Johnson, who lives in Pulaski County, Ky.

In Indiana, a toddler was found alone in a field near her family's home after a tornado hit in New Pekin. Authorities learned Saturday she is the sole survivor of her immediate family, said Cis Gruebbel, a spokeswoman for Kosair Children's Hospital in Louisville, Ky.

The girl's mother, father, 2-month-old sister and 2-year-old brother all died Friday, Washington County Coroner Rondale Brishaber said.She is in critical condition with extended family members at the hospital, and authorities are still trying to figure out how she ended up in the field.

"She is in extremely critical condition," Jack Brough, the girl's grandfather, told The Courier-Journal of Louisville. "She's had a lot of injuries to her head. The doctors told us that the next 24-48 hours are very critical."

About 20 miles east, a twister demolished Henryville, Ind., the birthplace of Kentucky Fried Chicken founder "Colonel" Harland Sanders. The second story of the elementary school was torn off, one of the city's three schools lost to weather; the punishing winds blew out the windows and gutted the Henryville Community Presbyterian Church.

A school secretary said a bus left the city's high school Friday afternoon with 11 children, but the driver turned back after realizing they were driving straight into the storm. The children hid under tables and desks at the school nurse's station when the tornado hit; none were hurt, but the building is a total loss.

The school bus was tossed several hundred yards into the side of a nearby restaurant. Todd and Julie Money were hiding there, having fled their Scottsburg home because it has no basement.

"Unreal. The pressure on your body, your ears pop, trees snap," Todd Money said. "When that bus hit the building, we thought it exploded."

The storms hit as far east as Ohio, where the Ohio River town of Moscow was so decimated that rugs hung from the trees.

"This half is gone and that half is damaged," said village native Steve Newberry, who was permitted into town Saturday to pick up medical supplies for his mother.

In Kentucky, the Rev. Kenneth Jett of the West Liberty United Methodist Church was huddling with four others in the basement as the church collapsed.

The pastor and his wife had just returned to the parsonage when he turned on the TV and saw that the storm was coming. Jett yelled to his wife to take shelter in the basement of the church next door, where they were joined by two congregants and a neighbor.

The last one down was Jett's wife, Jeanene.

"I just heard this terrific noise," she said. "The windows were blowing out as I came down the stairs."

The building collapsed, but they were able to get out through a basement door. They escaped with only bumps and bruises.

Janet Elliott was sitting on her bed in Chattanooga, Tenn., when a severe weather warning scrolled across the bottom of the screen. Fierce winds were blowing, and her cats seemed clingy. Her dogs had gotten low to the floor.

She ran to the basement and tried to pull the door shut, but she couldn't. She heard a ripping sound as the ceiling peeled off and wind wrenched the doorknob from her hand.

"I looked up and I could see the sky," she said. "I realized if I had stayed on the bed two seconds longer, I would have been sucked out or crushed."

In Washington County, Ind., residents saw a massive tornado come over a hill and plow through a grove of trees. When the winds had passed, it looked as if a line of bulldozers had rolled through.

Gene Lewellyn, his son and his son's 7-year-old daughter saw the tornado come over the hill, rushed to the basement of his one-story brick home and covered themselves with a carpet.

"It just shook once, and it (the house) was gone," said Lewellyn, 62, a retired press operator.

Friday's tornado outbreak had been forecast for days; meteorologists at the National Weather Service's Storm Prediction Center had said the day would be one of a handful this year that warranted its highest risk level. The weather service issued 297 tornado warnings and 388 severe thunderstorm warnings from Friday through early Saturday.

In April, when tornadoes killed more than 240 people in Alabama, it issued 688 tornado warnings and 757 severe thunderstorm warnings from Texas to New York, said Greg Carbin, warning coordination meteorologist at the storm prediction center.

It was a distinction without a difference for Lewellyn, who spent Saturday picking through the debris in 38-degree cold. His family was safe, but their home was reduced to a pile of bricks and sheet metal wrapped around splintered trees. Pieces of insulation coated the ground, and across the street a large trailer picked up by the storm had landed on top of a boat.

"Right now, we are not sure what we are going to do," he said. "We all get out what we can get out."

___

Suhr reported from New Pekin, Ind. Associated Press writers Kate Brumback in Chattanooga, Tenn., Tom LoBianco in Indianapolis and Bruce Schreiner in East Bernstadt, Ky., contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-03-03-Severe%20Weather/id-e59be033b84745e3ba31c2a976827268

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Sunday, March 4, 2012

Summary Box: Dow drops for the week; Yelp jumps (AP)

[unable to retrieve full-text content]AP - DOW 13K?: After closing above 13,000 earlier this week for the first time in nearly four years, the Dow ended the week lower for only the third time this year. It dropped 3 points Friday to close at 12,978.

Source: http://us.rd.yahoo.com/dailynews/rss/stocks/*http%3A//news.yahoo.com/s/ap/20120302/ap_on_bi_ge/us_wall_street_summary_box

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